E-HYPHEN-MAIL

etc. My wise friend Alex Boisvert noted that "ufology," the "study of ufos" works this way, but that's why I think "ufology" sounds like a made up word. I'm all for common usage ruling — Johnson complained about using 'fun' as a noun — but this is just a personal choice. Everybody in the world and all my descendents can go around "emailing" each other, but I'll always accidentally read that as "emmail". As for words like asymmetric, amorphous, and amoral, the "a" isn't an abbreviation, so I'm magically okay with this. ...equal, itinerary, oblique, usurp... Oh forget about it. (But I'll still hyphenate e-mail.)

The OED's non-committal opinion.